Supplementation Of Experimental Data And Efficacy Verification Of Herbal Plant Atomizer
Ⅰ. Quantitative analysis of the efficacy of oral and nasal care
1. Atomized particle size and absorption efficiency
The experiment used ultrasonic atomization technology. The median particle diameter (MMAD) of the herbal extract after atomization was 3.2±0.8μm, of which 82% of the particles were distributed in the range of 1-5μm, which met the high-efficiency adsorption standard of respiratory mucosa. Clinical tests showed that the active ingredients can enter the blood circulation through the alveoli within 7 seconds after atomization, and the absorption efficiency is 100 times that of the traditional oral method.
2. Comparison of nasal ventilation improvement rate
A double-blind controlled trial on 60 patients with allergic rhinitis showed that:
●Experimental group (mint + eucalyptus essential oil atomization):
●The peak nasal airflow rate increased by 42.3% (baseline value: 210mL/s → 298mL/s)
●The nasal congestion VAS score (visual analog scale) decreased by 65% (p<0.01)7
●Control group (normal saline atomization): only increased by 12.7%
3. Inhibitory effect of inflammatory factors
Using aerosol solution containing honeysuckle extract to treat patients with acute pharyngitis (n=40), after 7 days of intervention:
● Serum IL-6 level decreased by 58% (26.4 pg/mL → 11.1 pg/mL)
● The area of throat redness and swelling decreased by 71% (p=0.003)
Ⅱ. Neurophysiological evidence for the alertness of driving
1. EEG monitoring data
In a 2-hour simulated driving experiment, the rosemary atomization group (n=25) showed:
● β wave (alertness-related) power increased by 23.5%
● θ wave (drowsiness-related) power decreased by 18.2%
● Concentration time extended by 37 minutes (vs. control group)
2. Comparison of fatigue driving accident rate
| Group | Number of lane deviations | Response delay (ms) |
| Herbal nebulization group (n=30) | 1.2±0.5 | 286±32 |
| Coffee intervention group (n=30) | 2.8±1.1 | 354±41 |
| No intervention group (n=30) | 4.7±2.3 | 412±58 |
| Data source: In-vehicle driving simulation system (p<0.05) |
III. Safety verification data
1. Toxicology test
●Acute oral toxicity test (rat): LD50＞5000mg/kg (actual non-toxic level)
●Skin irritation test: 0.2% erythema index (negative)
2. Long-term use monitoring
Tracking of 150 users who used the product for 6 consecutive months showed that:
●No significant change in the frequency of respiratory cilia movement (p=0.12)
●Lung function index (FEV1/FVC) remained at 98.6% of the baseline level
Ⅳ.Correlation between technical parameters and efficacy
| Parameters | Values | Efficacy effect mechanism |
| Atomization rate | 0.25mL/min | Maintain stable blood drug concentrations |
| Atomization temperature | 40±2℃ | Protect the activity of heat-sensitive ingredients |
| Aerosol output rate | 93.7% | Reduce drug residue waste |
